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The cities with the most cases of bed bugs in the United States are Chicago, Detroit and Columbus, Ohio, according to a recent promotional study released by the pest control company Orkin. Orkin calculated the number of bed bug treatments it performed between January to December 2014, and ranked the cities based on how often they were called in. Having bed bugs doesn’t mean a living place is especially dirty, and any home or workplace is susceptible if bed bugs travel on clothing or in luggage. Citing data maintained by the pest control industry, Orkin says Americans spent around $446 million getting rid of bed bugs in 2013.

The bed bug business increased 18% last year, Orkin says. Here’s the full list of cities ranked from most to least cases of bed bugs: Chicago Detroit Columbus, Ohio Los Angeles Cleveland – Akron – Canton, Ohio Dallas – Ft. Worth Cincinnati Denver Richmond – Petersburg, Va. Dayton, Ohio Indianapolis Houston Seattle – Tacoma Washington, District of Columbia – Hagerstown, Md. Milwaukee San Francisco – Oakland – San Jose Raleigh – Durham – Fayetteville, N.C. New York Charleston – Huntington, W.Va. Grand Rapids – Kalamazoo – Battle Creek, Mich. Omaha, Neb.

Louisville, Ky. Nashville, Tenn. Lexington, Ky. Atlanta Buffalo, N.Y.

Sacramento – Stockton – Modesto, Calif. Syracuse, N.Y. Boston – Manchester Charlotte, N.C. Baltimore Phoenix – Prescott Miami – Ft. Lauderdale Knoxville, Tenn.

Cedar Rapids – Waterloo – Dubuque, Iowa Minneapolis – St. Paul Hartford – New Haven, Conn. Champaign – Springfield – Decatur, Ill. San Diego Lincoln – Hastings – Kearney, Neb. Kansas City, Mo.

Honolulu Albany – Schenectady – Troy, N.Y. Colorado Springs – Pueblo, Colo. Myrtle Beach – Florence, S.C. St. Louis Greenville – Spartanburg, S.C. – Asheville, N.C.

Bowling Green, Ky. Ft. Wayne, Ind. Toledo, Ohio This article originally appeared on Time.com.